IEEE Winnipeg Section


BME Seminar


Effect of saline infusion on obstructive sleep apnea severity in men


Thursday, Nov 21, 2013 from 5:30-6:30pm


EITC E2-330, University of Manitoba


Azadeh Yadollahi, Ph.D.


Recently, we have shown that sedentary living leads to excess fluid retention in the legs during the day and to a shift of this fluid when recumbent at night into the neck or chest, narrowing the airway, increasing airway resistance and predisposing to sleep apnea. In this talk, I will:

  1. review the current evidence for the role of rostral fluid shift on the pathogenesis of obstructive sleep apnea.
  2. describe the pattern of fluid redistribution in various body segments in men and women while supine, and
  3. describe the effect of intravenous saline infusion during sleep on the severity of obstructive sleep apnea in healthy men.

Speaker Bio:

Azadeh Yadollahi received her Ph.D. degree in biomedical engineering from the University of Manitoba in 2011 and she is currently a Postdoctoral fellow in the Institute of Biomaterial and Biomedical Engineering at the University of Toronto and an affiliated research scientist at the Toronto’s University Health Network-Toronto Rehabilitation Institute (UHN-TRI). Her Ph.D. research was very productive and led to registering one patent, publishing ten journal papers and receiving two prestigious awards: Philips Young Investigator Award and NSERC Innovation Challenge Award. Her current research at University of Toronto and UHN-TRI builds up on this foundation, to investigate how fluid accumulation in various body segments affects the pathogenesis of sleep apnea.