IEEE Orange County EMBS Chapter


Calendar of Events




  • Date: 29 Jul 2019
  • Time: 06:30 PM to 08:00 PM
  • 15500 Sand Canyon Ave, Irvine, California, United States 92618
    • Room Number: Community Meeting Room
  • Light dinner will be served


Despite the growing popularity of deep learning neural networks for various medical imaging applications, the vast majority of algorithms to date represent early proof-of-concept designs that will require a degree of evolution before achieving practical clinical utility. In this talk, we explore several different ways in which the current generation of deep learning applications can be advanced including:

(1) Reformulating the question: in medicine, there are often times more than one way to ask the same question—how do we reformulate a task in a way that both maximizes clinical utility and also best leverages the strength of various deep learning algorithms?

(2) Customizing deep learning algorithms: what are the unique technical challenges posed by medical imaging data and how we design custom deep learning architectures to account for them?

(3) Clinical implementation: what are some practical experiences learned from implementing deep learning tools in the clinical setting, and what are some regulatory hurdles that will need to be considered?


Peter D. Chang, MD of Co-Director, Center for Artificial Intelligence in Diagnostic Medicine UCI Health | Dept. of Radiologic Sci.


Dr.Chang’s unique perspective as both a physician and software engineer allows him to lead a team of engineers, data scientists, and clinicians to combine state-of-the-art techniques in machine learning with an intuitive understanding of the image interpretation process as a human radiologist. His work has yielded many collaborative efforts with principal investigators in multiple clinical specialties as well as many imaging departments across the United States and leadership roles in national and international organizations such as the American Society of Neuroradiology, Radiological Society of North America, and the International Society for Magnetic Resonance in Medicine. His software algorithms have been granted provisional patents and won multiple awards, including a first-place finish at the international 2016 MICCAI grand challenge for automated analysis of brain tumors. He has pursued a dedicated year of research in deep learning at the University of California San Francisco.

His primary insights arise from the ability to customize deep learning algorithms to the unique properties and goals of medical imaging data. He has extensive experience with the fundamental tools of deep learning including Python and Tensorflow, and has successfully written customized software for distributed file systems and GPU servers to process large-scale datasets including one million mammograms, 50,000 chest ICU films and 20,000 head CTs. In addition, he has broad expertise with the entire medical image processing pipeline including PACS networking and DICOM manipulation to efficiently generate large anonymized databases. He has integrated these databases into a customized web-based platform for efficient viewing and fast, large-scale annotation of medical images. Recently, his work has included the development of a novel hybrid 3D/2D architecture for detection of hemorrhage on non-contrast head CT, recording human-like performance at over 97% accuracy in a cohort of over 10,000 CTs [2]; this work was received the Cornelius G. Dyke Award for best scientific paper by an assistant professor (or below) in AJNR during 2017-18.






  • Date: 30 May 2019
  • Time: 06:30 PM to 08:00 PM
  • 15500 Sand Canyon Ave, Irvine, California, United States 92618
    • Room Number: Community Meeting Room
  • Light dinner will be served


Dr. Daniela Bota will talk about the Challenges and Novel Approaches in Brain cancer


Dr. Daniela Bota MD, PhD

Dr. Bota attended medical school in Bucharest then moved to California where she earned a PhD in molecular biology at the University of Southern California. She also trained as a neurologist and found herself drawn to patients who were fighting brain cancer. Dr. Daniela Bota is leading a phase 2 clinical trial of a glioblastoma vaccine made with white blood cells and protein antigens extracted from the patient’s tumor. The vaccine — made with the patient’s own activated white blood cells—is injected into the patient to help the immune system recognize and attack remaining cancer cells.


Distinguished Lecturers Program 5 June 2017

Light dinner to be provided

Register at:

TOPIC: Biosensors and their Applications

SPEAKER: Tom Jobe, Chief Operating Officer, SensiQ Technologies

President and Co-Founder – BioInSpire

IEEE Engineering in Medicine and Biology Society (EMBS) Distinguished Speaker


The talk will focus on the role of biosensors; a brief history followed by examples of how biosensors have become part of our everyday lives and how we will become integrated with them more and more in the future.

Tom Jobe – Chief Operating Officer – SensiQ Technologies, President and CoFounder – BioInSpire

Mr. Jobe holds  BS and MS Engineering degrees from Oklahoma State University. He spent 10 years in the energy business as an instrument developer and 15 years as a developer and manager of medical diagnostic instruments with Organon Teknika & BioMerieux, where he led the development of microbiology, coagulation, and nucleic acid diagnostics instrumentation. As Chief Operating Officer of SensiQ Technologies of Oklahoma City for the past 12 years, he has directed the R&D and Manufacturing operations for the company’s life sciences instrumentation and commercialization efforts. BioInspire provides marketing and commercialization services for Life Science companies as well job placement services for scientists and engineers.

The meeting time is 6:30 – 8 PM

Venue is Evonexus at 5151 California Ave Suite 150 Irvine 92617


FDA’s New Focus on Cybersecurity

Please join us for the joint presentation hosted by IEEE Orange County Computer Society (OCCS), The Orange County IEEE Cybersecurity Special Interest Group (CybersecuritySIG), and the Oranage County IEEE Engineering in Medicine & Biology Society (IEEE EMBS).


It’s no secret that he FDA has been focusing intensely on cybersecurity over the past couple of years.
The premarket and postmarket cybersecurity guidances put more responsibility on the manufacturerthan ever before, and many manufacturers are confused about what they need to do.
This talk will outline the current landscape and recent history explaining why the FDA is intensely
focusing on cybersecurity. It will also give recommendations and examples on the quickest way
for manufacturers to come up to speed with the guidances.

Date and Time

    • Date: 22 May 2017
    • Time: 06:30 PM to 08:30 PM
    • All times are US/Pacific


  • Chapman University
  • One University Drive
  • Orange, California
  • United States 92866
  • Building: building #25.
  • Room Number: Irvine Lecture Hall


  • Email event contact
  • Asad Abu-TarifPh.D., MBAPMP, MCSD, CSM, CTT+Chair, IEEE Orange County Computer Society (OCCS)VP, Research and DevelopmentMidmark Corporation
  • Co-sponsored by CybersecuritySIG, IEEE EMBS


  • Admission fee applies
  • Starts 07 May 2017 12:00 AM
  • Ends 22 May 2017 08:00 AM
  • All times are US/Pacific




Daniel Beard of Promenade Software, Inc.



FDA���s New Focus on Cybersecurity


6:30-7:00 Networking


7:00-8:00 Presentation


8:00-8:30 Questions and connecting with the speaker
Attendees can parking in the Lastinger Parking structure under the football field. The entrance in marked “LA” on the campus map.

See the Chapman campus map:

Orange County Section Chapter, C16 :


The New EU Medical Device Regulation – Overview for Engineers


6PM – 6:30 Networking

6:30pm -7:30 Presentation

Dinner will be provided at No cost

Will discuss on following topics:

–        Overview of the new rules (40,000’ view)

–        Focus on sections most likely to affect engineers

Revised essential requirements including suggestions for selecting standards

State of play of the harmonized standards

Expectations for field follow-up

–        Transition information (when will compliance be required)

  Date: 18 January 2017

  • 5151 California Ave, Suite 150
  • Irvine, California
  • United States 92617
  • Building: Evonexus
  • Email event contact
  • Harshad Parmar  949-973-1049

Co-sponsored by John Collins

  • No Admission Charge
  • Starts 04 December 2016 12:00 PM
  • Ends 18 January 2017 03:00 PM
  • All times are US/Pacific


Christine Ruther of IEEE Orange County EMBS Chapter


The New EU Medical Device Regulation – Overview for Engineers

Will discuss on following topics;

–        Overview of the new rules (40,000’ view)

–        Focus on sections most likely to affect engineers

          Revised essential requirements including suggestions for selecting standards

          State of play of the harmonized standards

          Expectations for field follow-up

         Transition information (when will compliance be required)


Christine Ruther received her undergraduate and graduate education in Ohio.  After completing a BS in Physics at Xavier University, she went on to earn a MS in Biomedical Engineering at The Ohio State University.  She is a licensed professional electrical engineer in California.

 Ms. Ruther has extensive experience in the medical device industry including experience with wireless devices.  She has significant strengths in compliance and regulatory engineering.  Ms. Ruther held the post of Director of Product Development and Regulatory Affairs for AirBed Corporation in Anaheim, California.  There she assisted in design of the company’s products, coordinated regulatory compliance and performed product failure analysis.  After working at AirBed, she joined TUV Product Service working from their San Diego, California, office.  At TUV, Christine was the technical manager for the Medical Device Testing group in the US and directly managed the Medical testing and ISO/CE auditing activities for the southwestern region.  As well as managing, Ms. Ruther specified and conducted compliance testing for medical devices and performed audits of medical device manufacturers.  After four years at TUV, Christine became the Compliance Manager for Cardiac Science in Irvine, California.  Her career advanced further when she joined the medical telemetry division of GE Medical Systems as a Lead Professional Systems Engineer.

 Ms. Ruther now works directly with a wide range of clients in compliance & safety engineering, and in quality & regulatory affairs.  She works mainly with manufacturers, from start-ups through Fortune 500 companies.  But, she has also worked for government agencies such as the National Institute of Standards and Technology (NIST) and the National Standards Authority of Ireland (NSAI), as well as standards and laboratory oversight agencies such as the American National Standards Institute (ANSI).  Her knowledge of global regulations from MDD/AIMDD and RED through FDA and FCC coupled with her engineering abilities in risk analysis and design controls makes her a valuable asset to device teams.

 Christine lives with her husband, Greg Adams, in Mission Viejo, California.  She has an active interest in professional organizations.  She volunteers with the local Institute of Electrical and Electronics Engineers (IEEE) chapter and other local groups.


6PM – 6:30 Networking

6:30pm -7:30 Presentation

Dinner will be provided at No cost

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Date: Wednesday, November 9th 2016

Speaker Name and Affiliation:
Christopher C.W. Hughes, Ph.D.
Professor & Francisco J. Ayala Chair
Department of Molecular Biology and
Biochemistry, Professor, Biomedical
Engineering, Director, Edwards Lifesciences
Center for Advanced Cardiovascular
Technology, UC Irvine
Human organs and their associated functions are, with few exceptions, 3-Dimensional, and so it
is hardly surprising that 2D cell culture systems often do a poor job at replicating human biology.
It is only the simplicity of 2D systems that has maintained their popularity for so long. We are
changing this dynamic – we can now create 3D tissues in the lab that share many of the
characteristics of organs in the body. Most importantly, the tissues receive their nutrients through
living blood vessels, just as they do in the body. This is a unique platform – we are the only lab in
the world able to do this.
We are creating multiple organs, including pancreas, brain, liver and heart, which we will use to
study diseases such as Diabetes, Alzheimer’s disease and Heart Failure. In addition, we have
created multiple types of micro-tumors, including colon, breast, prostate and melanoma, which
we are now using for novel drug screening.




IEEE Neural EngineeringWorkshop 2016

Networking Dinner/BBQ with a presentation on “Biomedical Commercialization” by Dr. Gary Fujii PhD, President and CEO of Molecular Express, located in Los Angeles, CA.

Wednesday, July 29th, 2015

Biography: Dr. Gary Fujii is President and CEO of Molecular Express a subsidiary of Molecular GPS Technologies™ which is a research and development technology company specializing in the application of life science technologies to address market needs across a broad spectrum of industries. The Company’s lipid and “Molecular Guided Particle System” (Molecular GPS™) delivery platform is the basis for many active programs targeting anti-cancer therapeutics, drug delivery systems, vaccines, and nanoparticulate drug delivery technologies. Dr. Fujii has extensive experience in formulating commercial liposome products and in membrane protein structure and function. He was formerly the Director of Gene Delivery for NeXstar Pharmaceuticals, Inc. (now Gilead Sciences, Inc.). Dr. Fujii received a Ph.D. in Physical Chemistry from the University of California, Los Angeles.

Abstract: The present system for commercializing biomedical research remains inefficient and underpowered. In this talk Dr. Fujii will describe the development of his biotech company, Molecular Express Inc that he grew in the last 20 years and address major issues in several stages of commercialization with his experience as an entrepreneur.

We hope you can join us at the EMBS Chapter Networking Dinner/BBQ with a presentation on “Biomedical Commercialization” by Dr. Gary Fujii PhD, President and CEO of Molecular Express, located in Los Angeles, CA.

The dinner and presentation is at Irvine Water District Facility Duck Club, 15 Riparian View, Irvine, CA on July 29th 2015.

Program for the event is as follows:

6-7 pm Networking BBQ

7-8 pm Presentation
Humanlike Robots – The Ultimate Challenge to Biomimetics by Yoseph Bar-Cohen, PhD, Senior Research Scientist and Group Supervisor, Jet Propulsion Laboratory (JPL), California Institute of Technology, Pasadena, CA

Wednesday, July 31st, 2014

Abstract: Biomimetics is the field of science and engineering that seeks to understand and use nature as a model for copying, adapting and inspiring concepts and designs. Evolution led to effective solutions to nature’s challenges that a continually being improved over millions of years. Humans have always made efforts to use nature as a model for innovation and problems solving. In recent years, these efforts have intensified where systematic studies are leading to better understanding of nature and to application of more sophisticated capabilities. As part of the field of biomimetics, scientists are seeking rules, concepts, mechanisms and principles of biology to inspire new engineering possibilities including methods of manufacturing, mechanisms, materials, processes, and algorithms.Some of the benefits that resulted are improved structures, actuators, sensors, interfaces, control, software, drugs, defense, intelligence and many others. The emergence of new technologies are enabling even further acceleration of the capability to mimic and be inspired by nature including the development of humanlike robots with capabilities that used to be considered science fiction ideas. In this lecture, the latest development, the potential and challenges will be reviewed and discussed.

Biography:Dr. Yoseph Bar-Cohen is a Senior Research Scientist and Supervisor of the Advanced Technologies Group at JPL. He received his Ph.D. in Physics (1979) from the Hebrew University, Jerusalem, Israel. His research is focused on electro-mechanics including planetary sample handling mechanisms, novel actuators that are driven by such materials as piezoelectric and EAP (also known as artificial muscles) and biomimetics. In his NDEAA lab, he led the development of many novel methods and mechanisms. In the materials called composites, he discovered the ultrasonic wave phenomena polar backscattering (1979) and leaky lamb waves (1983). He co-edited and co-authored 8 books, co-authored over 360 publications, made numerous presentations at national and international conferences, co-chaired 45 conferences, and has 25 registered patents. He initiated the SPIE conference on artificial muscles, which he has been chairing since 1999. Dr. Bar-Cohen challenged engineers and scientists worldwide to develop a robotic arm driven by artificial muscles to wrestle with humans and win. He organized the first wrestling contest in 2005. For his contributions to the field of artificial muscles, Business Week named him in April 2003 one of five technology gurus who are “Pushing Tech’s Boundaries.” His accomplishments earned him two NASA Honor Award Medals, two SPIE’s Lifetime Achievement Awards, the SPIE’s President’s Award and many other honors and awards. Also, he is a Fellow of two technical societies: ASNT and SPIE.
Program for the evening:

6:30-7:00pm Networking

7:00-8:00pm Presentation

Location: Brandman University, Room 111
16355 Laguna Canyon Road, Irvine, CA

Snacks will be provided
Educational Credit: With IEEE Educational Services all members participating in the EMBS presentation this year will be provided with ‘Professional Development Hours’ (PDH) credits
RSVP: Click here
Microengineered hydrogels for Stem Cell Bioengineering and Tissue Regeneration
Ali Khademhosseini, Ph.D.
Associate Professor at the Center for Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital; Harvard Medical School, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA
Micro- and nanoscale technologies are emerging as powerful tools for controlling the interaction between cells and their surroundings for biological studies, tissue engineering, and cell-based screening. In addition, hydrogel biomaterials have been increasingly used in various tissue engineering applications since they provide cells with a hydrated 3D microenvironment that mimics the native extracellular matrix. In our lab we have developed various approaches to merge microscale techniques with hydrogel biomaterials for directing stem cell differentiation and generating complex 3D tissues. In this talk, I will outline our work in controlling the cell-microenvironment interactions by using patterned hydrogels to direct the differentiation of stem cells. In addition, I will describe the fabrication and the use of microscale hydrogels for tissue engineering by using a ‘bottom-up’ and a ‘top-down’ approach. Top-down approaches for fabricating complex engineered tissues involve the use of miniaturization techniques to control cell-cell interactions or to recreate biomimetic microvascular networks. Our group has also pioneered bottom-up approaches to generate tissues by the assembly of shape-controlled cell-laden microgels (i.e. tissue building blocks), that resemble functional tissue units. In this approach, microgels were fabricated and induced to self assemble to generate 3D tissue structures with controlled microarchitecture and cell-cell interactions.
BiographyAli Khademhosseini is an Associate Professor at Harvard-MIT Division of Health Sciences and Technology, Brigham and Women’s Hospital and Harvard Medical School as well as an Associate Faculty at the Wyss Institute for Biologically Inspired Engineering and a Junior PI at Japan’s World Premier International-Advanced Institute for Materials Research at Tohoku University where he directs a satellite laboratory. He has authored 300+ journal papers (H-index = 57, >12700 citations) and 50 book chapters. In addition, he has been invited to 200+ invited/keynote lectures. Dr. Khademhosseini’s interdisciplinary research has been recognized by over 30 major national and international awards. He has received early career awards from three major engineering discipline societies: electrical (IEEE Engineering in Medicine and Biology Society award and IEEE Nanotechnology award), chemical (Colburn award from the AIChE) and mechanical engineering (Y.C. Fung award from the ASME). He is also a recipient of the Presidential Early Career Award for Scientists and Engineers, the highest honor given by the US government for early career investigators. He is a fellow of the American Institute of Medical and Biological Engineering (AIMBE) and the American Association for the Advancement of Science (AAAS). He is an Associate Editor for ACS Nano (IF: 12) and a standing member of NIH BTSS study section. He received his Ph.D. in bioengineering from MIT (2005), and MASc (2001) and BASc (1999) degrees from University of Toronto both in chemical engineering. Read more at:
Stem Cells: Cures or Clones?
Sidney H. Golub
Professor Emeritus, Microbiology & Molecular Genetics, School of Medicine

May 28 2014 at UCI

This talk will focus on the scientific basis for using stem cells and the prospects for clinical use of stem cells. The ethical challenges posed by stem cell research and the oversight mechanisms that have been developed will be discussed. The stem cell program at UCI will be described.

Biography: Dr. Golub obtained his B.S. from Brandeis University, his PH.D. from Temple University School of Medicine (1969) and was a Damon Runyon Fund Postdoctoral Scholar at the Dept. of Tumor Biology, Royal Karolinska Institute, Stockholm, Sweden (1969-1971) . He was on the faculty at the UCLA School of Medicine from 1971-1994 and at UCI from 1994 to the present. He was the Executive Director of The Federation of American Societies for Experimental Biology (FASEB) from 1999-2003.
My current interests focus on research ethics and science policy issues. I am particularly concerned with how we make and implement policy on human stem cells including embryonic and other pluripotent stem cells. One aspect of this interest is exploring the differences between California and the other states on stem cell policy. A related interest focuses on how to promote ethical principles within basic and translational research. My laboratory research program is not currently active. It followed two closely related themes: the in vitro regulation of cytotoxic cells by cell interactions, cytokines, and other regulatory factors and the in vivo expression of cytotoxic cell function in cancer patients. The major focus of these studies was on the regulation and expression of cytotoxicity by human Natural Killer (NK) lymphocytes including the function of lymphocytes at the tumor site (tumor infiltrating lymphocytes, or TILs) as these cells represent the immune response at the interface with the malignant cells.
Mobile Technology and Mobile Health- Disruptive Technology Meets Global Demand
, an IEEE Orange County EMBS Chapter Tech Talk

Speaker: Gora Datta, HL7 International Ambassador & co-Chair HL7 Mobile Health Work Group, IEEE Senior Member

Time and Place: Brandman University, Room 111,
16355 Laguna Canyon Road, Irvine, CA 92618
Nov 11, Monday, 6:00 – 8:00pm (light snacks and networking included)

Abstract: There has been a phenomenal rise of mobile devices and smartphones globally in the past few years. This global transformation is bringing a change that is impacting our world in every way – how we interact, play, read, write, watch, study, research, work or even relax. Traditional methods of doing research, developing solutions and subsequent adoption and utilization by end-users in this information and digital age at a break-neck speed is also seeing a change that is rapidly adapting/adopting to this wave. Regulators are scrambling to stay ahead of the curve by defining policies and regulations that will help leverage its benefits but at the same time, hopefully, not throttle or choke innovation. Mobile Health is in the midst of this explosion!
This talk will walk through Mobile Health case studies and implementation experiences from around the globe. The examples will demonstrate how health problems of today’s information society and the needs of data and knowledge intense heterogeneous but STANDARDS based healthcare solutions are being met by bleeding-edge mobile solutions that were in the cradle of research till recently. Think ATM for money, think WIFI for your laptops and smart phones working anywhere, think local cell phones working in a foreign land. STANDARDS are foundational to the global successes these industries have seen and this is the direction that health (IT) industry is taking.
In summary, as we transition to a digital record framework (access, capture, and dissemination of information) use of mobile health will continue to rise. As mobile devices become more and more ubiquitous, accessing our Health Information is only a few tap/swipe away!

Biography:Gora Datta, HL7 International Ambassador, is an accomplished, creative and visionary executive with over 29 years of international professional expertise in the field of Computer & Software Engineering and its application to Healthcare, eLearning & Social Protection. His global professional experience spans many countries – Australia, Bangladesh, Canada, France, Greece, India, Indonesia, Kuwait, New Zealand, Niger, Philippines, Singapore, Switzerland, Tunisia, UK, and USA.
He is the founding Chairman and CEO of CAL2CAL group of companies (estd. 1996 in California, USA: – a multi-national innovative m-ICT (mobile Information & Communication Technology) products and solutions organization with subsidiary and offices in Australia, India, & USA.
Gora is a Senior Member of both IEEE & ACM.
Industry Night hosted by IEEE EMBS Student Chapter at UCI
The UCI chapter of the IEEE Engineering in Medicine and Biology Society (EMBS) will host their inaugural Graduate Industry Night on Thursday, April 11, 2013 from 6-8 pm. If you or someone you know is looking to fill a technical role on your team with a MS or PhD-level biomedical engineer, or if you’re interested in scoping out collaboration opportunities with researchers in the BME department at UC Irvine, it’s our pleasure to invite you to campus.
Come meet graduating students with experience in biophotonics, biomaterials, microfluidics, tissue engineering, microfabrication, and cardiovascular device research. Tour our poster gallery, where students and faculty will be on hand to discuss their ongoing research projects and opportunities for collaboration. Light refreshments will be served.
Please extend this invitation to any colleagues who may be interested, and we look forward to meeting you at the event!